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Allergy and Immunology 

The Allergy and Immunology Department at SSM Health Cardinal Glennon Children’s Hospital is the only Pediatric Referral Program for Immune Deficiencies in Missouri.  Here, we provide comprehensive testing to determine whether or not your child has asthma, increased sensitivity to certain allergens, or a decreased ability to fight off infectious diseases.

Contact Us

To make an appointment, please call 314-268-4010.

We also serve Allergy patients at other SSM Health Cardinal Glennon locations in St. Louis, including SSM Health St. Joseph Hospital - Lake Saint Louis.

See more of our Close to Home locations here.

Common Diagnoses

Tests We Provide

Signs and Symptoms

Specialty Care Clinics

Preparing for Your Visit

Additional Resources

What to Expect from Your Visit

Meet the Team

Common Diagnoses

Adverse reaction to vaccines

Allergic rhinitis – swelling of the nasal lining resulting in "stuffy" or "runny" nose

Allergic bronchopulmonary aspergillosis – fungal infection resulting in inflammation of the lungs and airways

Allergic conjunctivitis

Anaphylaxis – allergic response involving hives, swelling, and lowered blood pressure


Atopic dermatitis (eczema)

Drug allergy

Eosinophilic esophagitis/gastroenteritis – inflammation of the esophagus or other parts of the digestive system

Food allergy

HIV infection and Acquired Immunodeficiency Disease (AIDS)

Hypersensitivity pneumonitis – heightened reaction to inhaled substances such as dust and chemicals

Immunodeficiency diseases –decreased ability to resist diseases

Insect allergy

Latex allergy

Non-allergic rhinitis

Sinusitis, fungal sinusitis – swelling of the tissue that lines the sinuses

Urticaria (hives)

Asthma may occur with physical exertion. In some cases, a child may be woken from sleep when experiencing symptoms. Signs of asthma include:

Shortness of breath



Preparing For Your Visit

Prior to the appointment, your child should stop taking all antihistamines, such as Claritin, Benadryl, Allegra, or Zyrtec for at least one week.

Your child’s initial visit to the Allergy Department will consist of a comprehensive analysis of his or her condition.  To ensure we are providing the best care for your child, the appointment may take a few hours.  For this reason, you may wish to bring something to entertain your child during that time.  You may also want to arrange for other children to stay home to make certain that your focus can be on the child experiencing symptoms. 

Parents are asked to bring previous medical records with them to the initial visit.  This saves time and can be very helpful in diagnosing a problem.  These records include:

Immunization history

Allergy testing results

Lab results

Medication records

What to Expect from Your Visit

When you arrive, you will be asked to register your child by verifying insurance information.  When that is complete, a Pediatric Clinical Partner will measure your child’s vital signs, height and weight.  After that, a nurse will go over the results and ask you and your child several questions about his or her symptoms and past/current medications.  A physician will then consult with you and your child and make recommendations for testing, which is typically done the same day as the appointment.

Tests We Provide

Allergy Skin Test – a non-painful (no needles) method of allergytesting.  Results are available within 20 minutes.

Pulmonary Function Test – breathing into a tube to assess lung function.  Results are available the same day. 

Patch Allergy Skin Test – specialized testing for food allergies.
Results generally take about four days.

Immune System Evaluation – series of blood tests.
Results usually take a few weeks to come back.

Radiologic Testing – exam of the sinuses and lungs.
Results are usually available within a day, but may take up to a week.

Jeffrey Modell Diagnostic Center for Primary Immunodeficiences

The Jeffrey Modell Diagnostic Center for Primary Immunodeficiencies sees patients with primary immune deficiency disorders. The goal of the center, created through the Jeffrey Modell Foundation, is to diagnose and treat patients with defects in the immune system that are carried through the genes. More than 150 immunodeficiencies have been identified to date, affecting more than 1 million Americans.

For a referral to the Jeffrey Modell Diagnostic Center at SSM Health Cardinal Glennon Children's Hospital, call 577-5600 ext. 4014.

Signs and Symptoms

These 10 warning signs of an immunodeficiency were developed by the Jeffrey Modell Foundation Medical Advisory Board:

Four or more new ear infections within 1 year

Two or more serious sinus infections within 1 year

Two or more months on antibiotics with little effect

Two or more pneumonias within 1 year

Failure of an infant to gain weight or grow normally

Recurrent, deep skin or organ abscesses

Persistent thrush in mouth or fungal infection on skin

Need for intravenous antibiotics to clear infections

Two or more deep-seated infections including septicemia

A family history of PI

Specialty Care Clinics

Allergy Challenge Clinic - perform controlled food and drug contact testing to evaluate for allergic diseases.

Asthma Center for Children - to provide ongoing care for pediatric asthma patients. 

Additional Resources

American Academy of Allergy, Asthma, and Immunology

American College of Allergy, Asthma, and Immunology

American Partnership for Eosinophilic Disorders

Jeffery Modell Foundation, Primary Immunodeficiency Resource Center

The Food Allergy and Anaphylaxis Network

Meet the Team

Alan Knutsen, MD, Director

Bradley Becker, MD

Manoj Warrier, MD

Wendy Sanders, BSN, RN
Research Nurse

Amanda Kerley, BSN, RN

Kelly Allison, BSN, RN

Melissa Bommarito, MSN, RN

Theresa Forsythe, Secretary

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